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Columbia University Researchers Study Living Samples in 3D

Columbia University Researchers Study Living Samples in 3D

Lambert Instruments is pleased to recognize the work described in a recent Nature Methods article authored by the research group of Professor Elizabeth Hillman at Columbia University in the City of New York. The researchers used SCAPE microscopy in combination with the Lambert Instruments HiCAM Fluo to achieve high-resolution volumetric imaging at over 300 volumes-per-second and over 1.2 GHz pixel rates.

Lambert Instruments Introduces sCMOS Camera for Effortless Scientific Imaging

Lambert sCMOS with lens.png

New camera combines excellent light sensitivity with automatic camera configuration

13 November 2018 - Groningen (NL) - Lambert Instruments today announced the introduction of a user-friendly sCMOS camera. The Lambert sCMOS automatically finds the optimal camera settings and captures excellent low-light images thanks to its advanced sCMOS image sensor.

Lambert sCMOS on microscope.png

With the Lambert sCMOS, Lambert Instruments aims to simplify image acquisition for scientific research, machine vision and industrial applications. "Researchers don't want to go through complicated camera configuration procedures before getting started with actually imaging their samples." says Jeroen Wehmeijer, Business Development Manager at Lambert Instruments. "That's why we paid a lot of attention to making the Lambert sCMOS a user-friendly scientific camera with great light sensitivity. The camera takes care of optimizing the images so the user can focus on their sample."

Automatic exposure and gain control adapt the camera configuration to match the current light conditions. And on-the-fly image correction and contrast enhancement ensure optimal image quality. In manual mode, users can fine-tune all camera settings for advanced applications that require quantitative image data.

The Lambert sCMOS features a 1280 x 1024 pixel sCMOS sensor that captures detailed images. Thanks to its excellent light sensitivity, the Lambert sCMOS captures up to 100 frames per second even under challenging low-light conditions.

With the Lambert Instruments Capture software, it is easy to record images and videos. Users can record, trim, analyze and export image data in widely supported image formats that are compatible with popular imaging platforms like Fiji/ImageJ.

For more information about the Lambert sCMOS, please visit or contact the Lambert Instruments sales team at or by calling +31 50 501 8461.

Lambert Instruments Introduces Toggel: A Next-Generation Fluorescence Lifetime Imaging Camera

New FLIM camera simplifies fluorescence lifetime imaging for researchers and imaging centers by combining excellent light sensitivity with easy image acquisition and data analysis.


5 April 2017 - Groningen (NL) - Lambert Instruments today announced the introduction of its next-generation fluorescence lifetime imaging camera: Toggel. This new camera makes fluorescence lifetime imaging microscopy (FLIM) and fluorescence resonance energy transfer (FRET) faster and easier with its excellent light sensitivity, sharp images and fast image acquisition.

With Toggel, Lambert Instruments aims to minimize measurement duration, automate image acquisition and simplify data analysis. These factors are of great importance to many of its customers in cell biology, cancer research and high-throughput screening.

"Toggel is the result of years of research and development." says Jasper Bosch, Development Engineer at Lambert Instruments. "From the start, we have collaborated with experts in FLIM and FRET at the Netherlands Cancer Institute, the University of Amsterdam and Delft University of Technology to make sure that this new camera fits the needs of our customers."

Toggel features a unique image sensor that was designed and optimized specifically for FLIM applications. This advanced sensor contains all the functionality required for fluorescence lifetime imaging, making the Toggel camera a solid-state FLIM camera and removing the need for an image intensifier. These technological improvements enable lifetime imaging at unprecedented frame rates with the single-image fluorescence lifetime imaging microscopy (siFLIM) method.*

"We used a prototype of this camera to develop a method for acquiring quantitative lifetime images from a single exposure." says professor Kees Jalink of the Netherlands Cancer Institute. "siFLIM takes advantage of the technical capabilities of this camera and simultaneously records two 180°-phase-shifted images. This allows for video-rate lifetime imaging with minimal phototoxicity and bleaching. siFLIM is also inherently immune to artifacts stemming from rapid cellular movements and signal transients."

Other imaging modes of the camera include regular frequency-domain FLIM acquisition and time-lapse recordings. Data analysis is done automatically by the Lambert Instruments software, which instantly calculates the fluorescence lifetime and presents it to the user as a colorized overlay on the original image.

For more information about Toggel, please visit or visit Lambert Instruments at booth 91 of the Focus On Microscopy conference in Bordeaux from 9-12 April.

* siFLIM: single-image frequency-domain FLIM provides fast and photon-efficient lifetime data, M. Raspe et al, Nature Methods 13, 501–504 (2016)

Toggel simplifies fluorescence lifetime imaging for researchers and imaging centers by combining excellent light sensitivity with easy image acquisition and data analysis.

Toggel simplifies fluorescence lifetime imaging for researchers and imaging centers by combining excellent light sensitivity with easy image acquisition and data analysis.

Lambert Instruments and FASTBASE SOLUTIONS Announce Strategic Partnership

FASTBASE SOLUTIONS implements a new cancer diagnostics platform based on proprietary technology delivered through the Lambert Instruments FLIM Attachment (LIFA) technology.

30 March 2017, Groningen (NL) - FASTBASE SOLUTIONS has developed a high specificity, super-sensitive, quantitative biomarker platform employing amplified FRET. This platform is designed to report on protein activation states and protein-complex formation in situ, such as in tumor biopsies. The mission of FASTBASE SOLUTIONS is to be the leading platform in cancer diagnostics, bringing precision to cancer patient treatment.

The image acquisition and analysis platform that FASTBASE SOLUTIONS employs is based on the fluorescence lifetime imaging technology developed by Lambert Instruments. Both parties have agreed to enter into a strategic partnership in order to successfully market FASTBASE SOLUTIONS technologies.

Professor Banafshé Larijani, CSO of FASTBASE: “The Lambert Instruments FLIM technology provides us with the tools we need to build our quantitative biomarker platform and accelerate our growth as a young company.”

Business Development Manager of Lambert Instruments, Jeroen Wehmeijer: “We are pleased to support Fastbase Solutions and their innovative applications of our FLIM technology.”

Find out more about the FASTBASE application at


About Lambert Instruments ( )
Lambert Instruments B.V., founded in 1992, located in Groningen, the Netherlands, develops advanced imaging solutions for low-light applications. Its flagship product is the Lambert Instruments FLIM Attachment (LIFA), which is a turn-key solution for fluorescence lifetime imaging microscopy (FLIM).  With end-users at all major universities and research institutes worldwide, Lambert Instruments has a solid reputation for high-end imaging solutions.

FASTBASE SOLUTIONS, is located in Bic Bizkaia 612, 48160 Derio, in the Basque Country, Spain. It was founded in 2016, by Peter J Parker, Banafshé Larijani, Pierre Leboucher and Antonio Ferrer. FASTBASE SOLUTIONS is implementing new technology to provide functional proteomics insights. This proprietary technology is delivered through the Lambert Instruments FLIM Attachment (LIFA) technology.  

Contact Information

Both Lambert Instruments and FASTBASE Solutions will be present during the Focus On Microscopy conference in Bordeaux at booth 91. For further information please contact Lambert Instruments at +31 50 501 8461.


Introducing the New TRiCAM

Lambert Instruments is proud to announce the next generation of its time-resolved intensified camera. The new TRiCAM is designed for scientific and industrial applications that require low-light imaging. It features a fast sensor, a high-performance image intensifier, and a redesigned aluminum enclosure.

Fast CMOS Sensor

The sensor in the new TRiCAM captures up to 160 frames per second at full resolution, and it can reach over 1000 fps at reduced resolution. Thanks to its electronic global shutter readout method, the sensor reads out all 2.3 million pixels at the same time. This prevents rolling shutter effects and ensures optimal image quality.

High-Performance Image Intensifier

Fiber-optically attached to the sensor is a high-performance image intensifier. This incredibly perceptive intensifier boosts the incoming light, allowing you to capture detailed images in the most challenging light conditions.

The built-in electronics offer a wide range of functionalities. Ultra-fast gating enables exposure times down to 3 nanoseconds. By precisely timing these exposures, the TRiCAM can be used for applications like time-gated luminescence and laser-induced fluorescence. With modulation frequencies up to 120 MHz, the TRiCAM is also ideal for a wide range of frequency-domain applications.

Redesigned Aluminum Enclosure

The aluminum enclosure of the TRiCAM has been redesigned from scratch. While remaining as compact as before, the TRiCAM can now be configured with an 18 mm intensifier or a 25 mm intensifier. It is compatible with both C-mount and F-mount input, and the standard tripod thread.

Machine Vision Standards

The TRiCAM is available with a USB3 or Ethernet interface. To provide optimal integration with your existing setup, it supports USB3 Vision and GigE machine vision standards.


The new TRiCAM is available as of today. Our experienced sales engineers are happy to assist you with choosing the right image intensifier for your application. Please contact our sales team or one of our distributors for more information.

Lambert Instruments Introduces New High-Speed Cameras

Lambert Instruments is proud to announce the introduction of a new line of high-speed cameras: The Lambert HS Series. The first cameras in the Lambert HS series feature a fast high-resolution sensor. The Lambert HS540M and the Lambert HS540S offer simple and efficient high-speed imaging for scientific research, R&D, machine vision and other industrial applications.

Lambert HS540M
The Lambert HS540M is a high-speed camera for research applications. It has up to 16 GB of internal storage and is ideal for scientific research and industrial R&D. After recording your data, you can review the results in our software and trim the high-speed video before exporting it to your computer.

Lambert HS540S
The Lambert HS540S is a streaming high-speed camera for industrial applications. It is designed for high-performance tasks like machine vision, quality control and wafer inspection. Instead of saving the images to internal storage, the camera streams high-speed video directly to your computer over a CoaXPress (CXP) interface. And with Power over CXP (PoCXP) the camera can be powered over the CoaXPress channels, removing the need for a dedicated power cable.

Fast High-Resolution Sensor
Both the Lambert HS540M and the HS540S feature a high-speed CMOS sensor that records full-resolution images (1696 x 1710 pixels) at 540 fps. To increase the framerate, the camera can use a smaller part of the sensor to reduce the image resolution. By doing so, it can deliver framerates of up to 170000 frames per second. Its electronic global shutter and minimum exposure time of 2 us ensure sharp images of fast-moving objects.

Digital Imaging Standards
The Lambert HS540 cameras support digital imaging standards that make it easy to integrate into an automated setup. The Generic Interface for Cameras (GenICam) offers a universal programming interface for controlling the camera settings and retrieving the recorded data. Camera characteristics are determined using the measurement procedures from the EMVA 1288 Standard. This makes specifications more transparent and easier to compare to other cameras.

New Business Location

New Business Location

Lambert Instruments is moving to a new location on May 1. Our new office building in Groningen is easier to reach for customers and it is more suited to accommodate our ongoing efforts to develop advanced imaging solutions.

Our new address is:

Lambert Instruments BV
Leonard Springerlaan 19
9727KB Groningen
The Netherlands

Our phone number will remain unchanged: +31 50 501 8461.

During this transition we might not respond to your emails as quickly as you're used to from us. We apologize for any inconvenience this might cause and will try to respond as soon as we can.

Introducing a Time-Domain FLIM Solution for Widefield Microscopes

Lambert Instruments is proud to introduce a new fluorescence lifetime imaging microscopy system: The Lambert Instruments FLIM Attachment for Time-Domain imaging. The LIFA-TD offers a turn-key solution for fluorescence lifetime imaging microscopy and is compatible with every widefield fluorescence microscope. From recording the data to calculating the fluorescence lifetime, the entire measurement procedure is automated by our advanced software.

The LIFA-TD includes a camera with a built-in image intensifier, which can precisely control the exposure of the camera. With its advanced gating capabilities, the image intensifier can reduce the exposure time to 3 ns and alter the timing of the exposure in the subnanosecond range.

A pulsed laser excites the fluorophores in the sample. By using a laser with a small pulse width, the accuracy of the lifetime measurements can be optimized.

Images are recorded with our advanced software, which also processes the data to determine the fluorescence lifetime. The fluorescence lifetimes are then shown as a colorized overlay on the original image.

Mastering Sustained Megahertz Gating

Lambert Instruments announces a brand new megahertz gate unit for its intensified high-speed imaging products. The Lambert Instruments megahertz gate unit is a high-voltage pulse generator that generates up to a million high-voltage pulses per second. These pulses are sent to an image intensifier, enabling high-resolution gated imaging for applications like time-domain fluorescence lifetime imaging and single-photon detection.

The megahertz gate unit is an important step forward in intensifier gating, as it supports continuous operation at 1 MHz. The advanced pulse generator provides optimal image intensifier operation at all repetition rates, even at the peak repetition rate. This high-quality signal further improves the imaging results of Lambert Instruments intensified imaging solutions.

For more information, please contact our sales team.

Lambert Instruments Ships First LIFA to India

Lambert Instruments is proud to announce the shipment of the first LIFA to India, following our increased effort to meet the growing demand for scientific imaging equipment in Asia.

Professor Inamdar studies quantum-dot-based FRET at Karnatak University in Dharwad, India. His interest in the LIFA was sparked by its ability to quickly measure fluorescence lifetimes. "We used to do FRET measurements using fluorescence intensities," says professor Inamdar, "but with ratiometric techniques you can't measure fluorescence lifetimes. So we started looking for a FLIM system, because fluorescence lifetimes are very useful for our kind of work."

With the LIFA, Inamdar hopes to advance his research and extend it to biological applications. The LIFA is the ideal solution for such applications, because it can record a lifetime image in a matter of seconds, practically making the process a real-time experience.

Inamdar was supported by Dynotech Instruments during the purchase process. Dynotech Instruments is a leading supplier of products and solutions in the field of optics in India, including Lambert Instruments products.

From 23rd to 25th of September, Lambert Instruments and Dynotech Instruments will be at the Laser World of Photonics 2014 in Bangalore. Visit us at booth B006 in hall 3A for more information about the LIFA and our other products.

Change of ownership

Starting from May 2nd 2013, our director Bert van Geest retired from Lambert Instruments BV. The company has been sold to a new owner and will be directed by Mr. Gerard Verheule as CEO. Gerard has a long background in technical commercial activities as owner and director of several wholesale companies in electrotechnical and electronic products. He will continue Lambert Instruments BV in its current state including staff and facilities.

The company will continue to focus on the development, production and worldwide sales of high-end products for time-resolved imaging at low light levels, including intensified High-Speed cameras and FLIM systems, guided by customer feedback. A smooth transition will be assured by the services of Bert van Geest as an advisor.